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Symbol
Name
ID
Plp1
proteolipid protein (myelin) 1
MGI:97623
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Recurrent respiratory infections
Disease(s) Associated with PLP1
hereditary spastic paraplegia 2
Pelizaeus-Merzbacher disease

Mouse Phenotypes
increased T cell number
abnormal microglial cell morphology
microgliosis
decreased susceptibility to Picornaviridae infection
Availability Mouse Genotype
Plp1jp-rsh/Plp1jp-rsh
Plp1jp-rsh/Plp1+
Plp1tm1Kan/Y
Plp1tm1c(EUCOMM)Wtsi/Y
Cnptm1(cre)Kan/Cnp+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory